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Mitochondrial Oxidative Stress Induces Cardiac Fibrosis in Obese Rats through Modulation of Transthyretin
A proteomic approach was used to characterize potential mediators involved in the improvement in cardiac fibrosis observed with the administration of the mitochondrial antioxidant MitoQ in obese rats. Male Wistar rats were fed a standard diet (3.5% fat; CT) or a high-fat diet (35% fat; HFD) and trea...
Autores principales: | Martínez-Martínez, Ernesto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Nieto, María Luisa, Bravo-San Pedro, José Manuel, Cachofeiro, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330867/ https://www.ncbi.nlm.nih.gov/pubmed/35897655 http://dx.doi.org/10.3390/ijms23158080 |
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