Cisplatin Effects on the Human Fetal Testis – Establishing the Sensitive Period for (Pre)Spermatogonial Loss and Relevance for Fertility Preservation in Pre-Pubertal Boys

BACKGROUND: Exposure to chemotherapy during childhood can impair future fertility. Studies using in vitro culture have shown exposure to platinum-based alkylating-like chemotherapy reduces the germ cell number in the human fetal testicular tissues. We aimed to determine whether effects of exposure t...

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Detalles Bibliográficos
Autores principales: Matilionyte, Gabriele, Rimmer, Michael P., Spears, Norah, Anderson, Richard A., Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330899/
https://www.ncbi.nlm.nih.gov/pubmed/35909565
http://dx.doi.org/10.3389/fendo.2022.914443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330899/
https://www.ncbi.nlm.nih.gov/pubmed/35909565
http://dx.doi.org/10.3389/fendo.2022.914443

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