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Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis

BACKGROUND: Treatment of neonatal peritonitis and sepsis is challenging. Following infection, neutrophils elaborate neutrophil extracellular traps (NETs)—extracellular lattices of decondensed chromatin decorated with antimicrobial proteins. NETs, however, can augment pathogenic inflammation causing...

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Detalles Bibliográficos
Autores principales: Denorme, Frederik, Rustad, John L., Portier, Irina, Crandell, Jacob L., de Araujo, Claudia V., Cody, Mark J., Campbell, Robert A., Yost, Christian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331023/
https://www.ncbi.nlm.nih.gov/pubmed/35902703
http://dx.doi.org/10.1038/s41390-022-02219-0