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Reducing White Adipose Tissue Browning Using p38α MAPK Inhibitors Ameliorates Cancer-Associated Cachexia as Assessed by Magnetic Resonance Imaging

Background: Up to 80% of pancreatic cancer patients suffer from cachexia. White adipose tissue (WAT) browning caused by the tumorigenicity and progression aggravates the cancer-associated cachexia (CAC). Cancer-initiated changes in the protein-38 mitogen-activated protein kinases (p38 MAPK) pathway...

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Detalles Bibliográficos
Autores principales: Zhao, Yufei, Dai, Jingyue, Jiang, Yang, Wu, Honghong, Cui, Ying, Li, Xinxiang, Mao, Hui, Wang, Binghui, Ju, Shenghong, Peng, Xin-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331061/
https://www.ncbi.nlm.nih.gov/pubmed/35893867
http://dx.doi.org/10.3390/nu14153013