Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

Exposure to environmental mutagens increases the risk of cancer and genetic disorders. We used Duplex Sequencing (DS), a high-accuracy error-corrected sequencing technology, to analyze mutation induction across twenty 2.4 kb intergenic and genic targets in the bone marrow of MutaMouse males exposed...

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Detalles Bibliográficos
Autores principales: LeBlanc, Danielle P. M., Meier, Matthew, Lo, Fang Yin, Schmidt, Elizabeth, Valentine, Charles, Williams, Andrew, Salk, Jesse J., Yauk, Carole L., Marchetti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331077/
https://www.ncbi.nlm.nih.gov/pubmed/35902794
http://dx.doi.org/10.1186/s12864-022-08752-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331077/
https://www.ncbi.nlm.nih.gov/pubmed/35902794
http://dx.doi.org/10.1186/s12864-022-08752-w

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