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Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges

Multiple myeloma (MM) is an incurable plasma cell malignancy with a heterogeneous genetic background. Each MM subtype may have its own therapeutic vulnerabilities, and tailored therapy could improve outcomes. However, the cumulative frequency of druggable targets across patients is very low, which h...

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Detalles Bibliográficos
Autores principales: Sklavenitis-Pistofidis, Romanos, Getz, Gad, Ghobrial, Irene, Papaioannou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331166/
https://www.ncbi.nlm.nih.gov/pubmed/35912171
http://dx.doi.org/10.3389/fonc.2022.961421