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Combined effect of pancreatic lipid content and gene variants (TCF7L2, WFS1 and 11BHSD1) on B-cell function in Middle Aged Women in a Post Hoc Analysis

BACKGROUND: TCF7L2 rs7903146 and PNPLA3 rs738409 gene variants confer the strongest risk for type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD), respectively. Pancreatic triacylglycerol content (PTGC) was reported to have a role in T2DM development. We aimed to assess the...

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Detalles Bibliográficos
Autores principales: Nádasdi, Ákos, Gál, Viktor, Masszi, Tamás, Patócs, Attila, Igaz, Peter, Somogyi, Anikó, Firneisz, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331183/
https://www.ncbi.nlm.nih.gov/pubmed/35897035
http://dx.doi.org/10.1186/s13098-022-00876-z