Precision Medicine Highlights Dysregulation of the CDK4/6 Cell Cycle Regulatory Pathway in Pediatric, Adolescents and Young Adult Sarcomas

SIMPLE SUMMARY: This review provides an overview of clinical features and current therapies in children, adolescents, and young adults (AYA) with sarcoma. It highlights the basic and clinical findings on the cyclin-dependent kinases 4 and 6 (CDK4/6) cell cycle regulatory pathway in the context of th...

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Detalles Bibliográficos
Autores principales: Barghi, Farinaz, Shannon, Harlan E., Saadatzadeh, M. Reza, Bailey, Barbara J., Riyahi, Niknam, Bijangi-Vishehsaraei, Khadijeh, Just, Marissa, Ferguson, Michael J., Pandya, Pankita H., Pollok, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331212/
https://www.ncbi.nlm.nih.gov/pubmed/35892870
http://dx.doi.org/10.3390/cancers14153611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331212/
https://www.ncbi.nlm.nih.gov/pubmed/35892870
http://dx.doi.org/10.3390/cancers14153611

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