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Precision Medicine Highlights Dysregulation of the CDK4/6 Cell Cycle Regulatory Pathway in Pediatric, Adolescents and Young Adult Sarcomas
SIMPLE SUMMARY: This review provides an overview of clinical features and current therapies in children, adolescents, and young adults (AYA) with sarcoma. It highlights the basic and clinical findings on the cyclin-dependent kinases 4 and 6 (CDK4/6) cell cycle regulatory pathway in the context of th...
Autores principales: | Barghi, Farinaz, Shannon, Harlan E., Saadatzadeh, M. Reza, Bailey, Barbara J., Riyahi, Niknam, Bijangi-Vishehsaraei, Khadijeh, Just, Marissa, Ferguson, Michael J., Pandya, Pankita H., Pollok, Karen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331212/ https://www.ncbi.nlm.nih.gov/pubmed/35892870 http://dx.doi.org/10.3390/cancers14153611 |
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