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MHC-independent αβT cells: Lessons learned about thymic selection and MHC-restriction
Understanding the generation of an MHC-restricted T cell repertoire is the cornerstone of modern T cell immunology. The unique ability of αβT cells to only recognize peptide antigens presented by MHC molecules but not conformational antigens is referred to as MHC restriction. How MHC restriction is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331304/ https://www.ncbi.nlm.nih.gov/pubmed/35911724 http://dx.doi.org/10.3389/fimmu.2022.953160 |