Cargando…

MHC-independent αβT cells: Lessons learned about thymic selection and MHC-restriction

Understanding the generation of an MHC-restricted T cell repertoire is the cornerstone of modern T cell immunology. The unique ability of αβT cells to only recognize peptide antigens presented by MHC molecules but not conformational antigens is referred to as MHC restriction. How MHC restriction is...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Laethem, François, Bhattacharya, Abhisek, Craveiro, Marco, Lu, Jinghua, Sun, Peter D., Singer, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331304/
https://www.ncbi.nlm.nih.gov/pubmed/35911724
http://dx.doi.org/10.3389/fimmu.2022.953160