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Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of Leishmania major Infection

Interleukin (IL)-4 plays a central role in the initiation of a type 2 T helper cell (Th2) response, which leads to non-healing and progressive infections with the protozoan parasite Leishmania (L.) major. Here, we tested the hypothesis that type 2 innate lymphoid cells (ILC2), which promote the deve...

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Detalles Bibliográficos
Autores principales: Sasse, Carolin, Barinberg, David, Obermeyer, Stephanie, Debus, Andrea, Schleicher, Ulrike, Bogdan, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331382/
https://www.ncbi.nlm.nih.gov/pubmed/35894051
http://dx.doi.org/10.3390/pathogens11080828