Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis

Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) has been the primary interest among studies on antiviral discovery, viral replication kinetics, drug resistance, and viral evolution. Following infection and entry into target cells, the HIV-1 core disassembles, and the viral RT...

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Detalles Bibliográficos
Autores principales: Bowen, Nicole E., Oo, Adrian, Kim, Baek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331428/
https://www.ncbi.nlm.nih.gov/pubmed/35893688
http://dx.doi.org/10.3390/v14081622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331428/
https://www.ncbi.nlm.nih.gov/pubmed/35893688
http://dx.doi.org/10.3390/v14081622

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