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Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells

Dimethyl sulfoxide (DMSO) is used to sustain or favor hepatocyte differentiation in vitro. Thus, DMSO is used in the differentiation protocol of the HepaRG cells that present the closest drug-metabolizing enzyme activities to primary human hepatocytes in culture. The aim of our study is to clarify i...

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Detalles Bibliográficos
Autores principales: Dubois-Pot-Schneider, Hélène, Aninat, Caroline, Kattler, Kathrin, Fekir, Karim, Jarnouen, Kathleen, Cerec, Virginie, Glaise, Denise, Salhab, Abdulrahman, Gasparoni, Gilles, Takashi, Kubo, Ishida, Seiichi, Walter, Jörn, Corlu, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331440/
https://www.ncbi.nlm.nih.gov/pubmed/35892596
http://dx.doi.org/10.3390/cells11152298