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Alterations of autophagic and innate immune responses by the Crohn’s disease-associated ATG16L1 mutation
Crohn’s disease (CD) is driven by the loss of tolerance to intestinal microbiota and excessive production of pro-inflammatory cytokines. These pro-inflammatory cytokines are produced by macrophages and dendritic cells (DCs) upon sensing the intestinal microbiota by the pattern recognition receptors...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331526/ https://www.ncbi.nlm.nih.gov/pubmed/36051337 http://dx.doi.org/10.3748/wjg.v28.i26.3063 |