Alterations of autophagic and innate immune responses by the Crohn’s disease-associated ATG16L1 mutation

Crohn’s disease (CD) is driven by the loss of tolerance to intestinal microbiota and excessive production of pro-inflammatory cytokines. These pro-inflammatory cytokines are produced by macrophages and dendritic cells (DCs) upon sensing the intestinal microbiota by the pattern recognition receptors...

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Detalles Bibliográficos
Autores principales: Okai, Natsuki, Watanabe, Tomohiro, Minaga, Kosuke, Kamata, Ken, Honjo, Hajime, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331526/
https://www.ncbi.nlm.nih.gov/pubmed/36051337
http://dx.doi.org/10.3748/wjg.v28.i26.3063

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