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Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic Cancer (PC) is one of the most lethal cancers. PC promotes the expansion of immunosuppressive Myeloid-Derived Suppressor Cells (MDSC) and Tumor Associated Macrophages (TAM) that dampen anti-tumor immunity and renders immunotherapies ineffective. We have identified Src Homo...

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Detalles Bibliográficos
Autores principales: Husain, Kazim, Villalobos-Ayala, Krystal, Laverde, Valentina, Vazquez, Oscar A., Miller, Bradley, Kazim, Samra, Blanck, George, Hibbs, Margaret L., Krystal, Gerald, Elhussin, Isra, Mori, Joakin, Yates, Clayton, Ghansah, Tomar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331563/
https://www.ncbi.nlm.nih.gov/pubmed/35892872
http://dx.doi.org/10.3390/cancers14153613