Cargando…
Cancer-Associated Mutations of the Adenosine A(2A) Receptor Have Diverse Influences on Ligand Binding and Receptor Functions
The adenosine A(2A) receptor (A(2A)AR) is a class A G-protein-coupled receptor (GPCR). It is an immune checkpoint in the tumor micro-environment and has become an emerging target for cancer treatment. In this study, we aimed to explore the effects of cancer-patient-derived A(2A)AR mutations on ligan...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331671/ https://www.ncbi.nlm.nih.gov/pubmed/35897852 http://dx.doi.org/10.3390/molecules27154676 |