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Nucleoside Transport and Nucleobase Uptake Null Mutants in Leishmania mexicana for the Routine Expression and Characterization of Purine and Pyrimidine Transporters

The study of transporters is highly challenging, as they cannot be isolated or studied in suspension, requiring a cellular or vesicular system, and, when mediated by more than one carrier, difficult to interpret. Nucleoside analogues are important drug candidates, and all protozoan pathogens express...

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Detalles Bibliográficos
Autores principales: Aldfer, Mustafa M., AlSiari, Tahani A., Elati, Hamza A. A., Natto, Manal J., Alfayez, Ibrahim A., Campagnaro, Gustavo D., Sani, Bashiru, Burchmore, Richard J. S., Diallinas, George, De Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331716/
https://www.ncbi.nlm.nih.gov/pubmed/35897714
http://dx.doi.org/10.3390/ijms23158139