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Lipopolysaccharide Exposure Differentially Alters Plasma and Brain Inflammatory Markers in Adult Male and Female Rats

Humans and rodents have sexually dimorphic immune responses, which could influence the brain’s response to a systemic inflammatory insult. Lipopolysaccharide (LPS) is a stimulator of the innate immune system and is routinely used in animal models to study blood–brain barrier (BBB) dysfunction under...

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Detalles Bibliográficos
Autores principales: Nonoguchi, Hannah A., Kouo, Timothy Wee Shang, Kortagere, Sandhya, Hillman, Joshua, Boyle, David L., Mandyam, Chitra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331770/
https://www.ncbi.nlm.nih.gov/pubmed/35892413
http://dx.doi.org/10.3390/brainsci12080972