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A Genome-Wide CRISPR Screen Identifies Factors Regulating Pluripotency Exit in Mouse Embryonic Stem Cells

Pluripotency maintenance and exit in embryonic stem cells is a focal topic in stem cell biology. However, the effects of screening under very stringent culture conditions (e.g., differentiation medium, no leukemia inhibitory factor, no chemical inhibitors such as PD0325901 and CHIR99021, and no feed...

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Detalles Bibliográficos
Autores principales: Gao, Chen, Qi, Xiaolan, Gao, Xin, Li, Jin, Qin, Yumin, Yin, Yunjun, Gao, Fei, Feng, Tao, Wu, Sen, Du, Xuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331787/
https://www.ncbi.nlm.nih.gov/pubmed/35892587
http://dx.doi.org/10.3390/cells11152289