Cargando…

A Genome-Wide CRISPR Screen Identifies Factors Regulating Pluripotency Exit in Mouse Embryonic Stem Cells

Pluripotency maintenance and exit in embryonic stem cells is a focal topic in stem cell biology. However, the effects of screening under very stringent culture conditions (e.g., differentiation medium, no leukemia inhibitory factor, no chemical inhibitors such as PD0325901 and CHIR99021, and no feed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Chen, Qi, Xiaolan, Gao, Xin, Li, Jin, Qin, Yumin, Yin, Yunjun, Gao, Fei, Feng, Tao, Wu, Sen, Du, Xuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331787/ https://www.ncbi.nlm.nih.gov/pubmed/35892587 http://dx.doi.org/10.3390/cells11152289

Ejemplares similares

Single cell lineage analysis of mouse embryonic stem cells at the exit from pluripotency
por: Trott, Jamie, et al.
Publicado: (2013)

Derivation of transgene-free bat induced pluripotent stem cells amenable to chimera formation in mice, pigs, and chicks
por: Qin, Yumin, et al.
Publicado: (2023)

Genome‐scale screening in a rat haploid system identifies Thop1 as a modulator of pluripotency exit
por: Xu, Mei, et al.
Publicado: (2022)

TSA Activates Pluripotency Factors in Porcine Recloned Embryos
por: Feng, Tao, et al.
Publicado: (2022)

Dicer, a new regulator of pluripotency exit and LINE‐1 elements in mouse embryonic stem cells
por: Bodak, Maxime, et al.
Publicado: (2017)

Plpp3, a novel regulator of pluripotency exit and endodermal differentiation of mouse embryonic stem cells
por: Montané-Romero, Martha E., et al.
Publicado: (2023)

Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo
por: Mulas, Carla, et al.
Publicado: (2018)

Epsins Regulate Mouse Embryonic Stem Cell Exit from Pluripotency and Neural Commitment by Controlling Notch Activation
por: Cardano, Marina, et al.
Publicado: (2019)

Screening Genes Promoting Exit from Naive Pluripotency Based on Genome-Scale CRISPR-Cas9 Knockout
por: Yang, Bin, et al.
Publicado: (2020)

Jun‐Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency
por: Veluscek, Giulia, et al.
Publicado: (2016)

Embryonic stem cells become mechanoresponsive upon exit from ground state of pluripotency
por: Verstreken, C. M., et al.
Publicado: (2019)

Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation
por: Li, Qing V., et al.
Publicado: (2019)

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency
por: Haswell, Jeffrey R., et al.
Publicado: (2021)

Taking the RISC of exiting naïve pluripotency
por: Guallar, Diana, et al.
Publicado: (2016)

MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
por: Bahat, Amir, et al.
Publicado: (2018)

Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state
por: Navarra, Angelica, et al.
Publicado: (2016)

N6-methyladenosine (m(6)A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
por: Jin, Kang-Xuan, et al.
Publicado: (2021)

Directed Differentiation of Zebrafish Pluripotent Embryonic Cells to Functional Cardiomyocytes
por: Xiao, Yao, et al.
Publicado: (2016)

Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion
por: Popa, Stephanie, et al.
Publicado: (2020)

Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses
por: Tian, Xuezhang, et al.
Publicado: (2023)

Genome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth
por: Wang, Yu, et al.
Publicado: (2019)

A HIT-trapping strategy for rapid generation of reversible and conditional alleles using a universal donor
por: Lu, Hengxing, et al.
Publicado: (2021)

Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture
por: Wang, Yichen, et al.
Publicado: (2022)

STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells
por: Peng, Tianran, et al.
Publicado: (2020)

Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency
por: Singh, Amar M., et al.
Publicado: (2015)

Genome-wide shRNA screening to identify factors mediating Gata6 repression in mouse embryonic stem cells
por: Cooper, Sarah, et al.
Publicado: (2013)

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells
por: Stryjewska, Agata, et al.
Publicado: (2016)

Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer
por: Feng, Junru, et al.
Publicado: (2022)

High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells
por: Li, Hui, et al.
Publicado: (2017)

Genome-wide CRISPR screen identified Rad18 as a determinant of doxorubicin sensitivity in osteosarcoma
por: Du, Mingrui, et al.
Publicado: (2022)

Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells
por: Alda-Catalinas, Celia, et al.
Publicado: (2021)

Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells
por: Bar, Shiran, et al.
Publicado: (2021)

CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
por: Qi, Shutao, et al.
Publicado: (2022)

The birth of embryonic pluripotency
por: Boroviak, Thorsten, et al.
Publicado: (2014)

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation
por: Westerman, Bart A., et al.
Publicado: (2011)

Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia
por: Jiang, Chuang, et al.
Publicado: (2022)

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening
por: Williams, Charles A. C., et al.
Publicado: (2017)

Cell cycle heterogeneity directs spontaneous 2C state entry and exit in mouse embryonic stem cells
por: Zhu, Yuqing, et al.
Publicado: (2021)

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency
por: Rulands, Steffen, et al.
Publicado: (2018)

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors
por: Schleicher, Emily M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vhti8k5r15lugic7dm97fnvqi4