Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing TNFSF11 expression and inhibiting PI3K/AKT/mTOR signaling in cartilage

Osteoarthritis (OA) is a widespread chronic degenerative joint disease characterized by the degeneration of articular cartilage or inflamed joints. Our findings indicated that treatment with artemisinin (AT) downregulates the protein levels of MMP3, MMP13, and ADAMTS5, which are cartilage degradatio...

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Detalles Bibliográficos
Autores principales: Li, Jin, Jiang, Mengqing, Yu, Zhentang, Xiong, Chenwei, Pan, Jieen, Cai, Zhenhai, Xu, Nanwei, Zhou, Xindie, Huang, Yong, Yang, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331798/
https://www.ncbi.nlm.nih.gov/pubmed/35902802
http://dx.doi.org/10.1186/s11658-022-00365-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331798/
https://www.ncbi.nlm.nih.gov/pubmed/35902802
http://dx.doi.org/10.1186/s11658-022-00365-1

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