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A Direct Interaction between Cyclodextrins and TASK Channels Decreases the Leak Current in Cerebellar Granule Neurons

SIMPLE SUMMARY: Cyclodextrins are cyclic oligosaccharides used to deplete cholesterol from cellular membranes. The effects of methyl-β-cyclodextrin (MβCD) on cellular functions originate principally from reductions in cholesterol levels. In this study, using immunocytochemistry, heterologous express...

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Detalles Bibliográficos
Autores principales: Zúñiga, Rafael, Mancilla, Daniel, Rojas, Tamara, Vergara, Fernando, González, Wendy, Catalán, Marcelo A., Zúñiga, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331813/
https://www.ncbi.nlm.nih.gov/pubmed/35892953
http://dx.doi.org/10.3390/biology11081097