Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits

Nemaline myopathy (NM) is characterized by skeletal muscle weakness and atrophy. No curative treatments exist for this debilitating disease. NM is caused by mutations in proteins involved in thin-filament function, turnover, and maintenance. Mutations in nebulin, encoded by NEB, are the most common...

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Detalles Bibliográficos
Autores principales: Lindqvist, Johan, Kolb, Justin, de Winter, Josine, Tonino, Paola, Hourani, Zaynab, Labeit, Siegfried, Ottenheijm, Coen, Granzier, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331820/
https://www.ncbi.nlm.nih.gov/pubmed/35897687
http://dx.doi.org/10.3390/ijms23158113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331820/
https://www.ncbi.nlm.nih.gov/pubmed/35897687
http://dx.doi.org/10.3390/ijms23158113

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