Digitoxin Affects Metabolism, ROS Production and Proliferation in Pancreatic Cancer Cells Differently Depending on the Cell Phenotype

Digitoxin has repeatedly shown to have negative effects on cancer cell viability; however, the actual mechanism is still unknown. In this study, we investigated the effects of digitoxin (1–100 nM) in four pancreatic cancer cell lines, BxPC-3, CFPAC-1, Panc-1, and AsPC-1. The cell lines differ in the...

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Detalles Bibliográficos
Autores principales: Lindholm, Heléne, Ejeskär, Katarina, Szekeres, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331846/
https://www.ncbi.nlm.nih.gov/pubmed/35897809
http://dx.doi.org/10.3390/ijms23158237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331846/
https://www.ncbi.nlm.nih.gov/pubmed/35897809
http://dx.doi.org/10.3390/ijms23158237

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