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Levamisole Suppresses CD4(+) T-Cell Proliferation and Antigen-Presenting Cell Activation in Aplastic Anemia by Regulating the JAK/STAT and TLR Signaling Pathways

Aplastic anemia (AA) is a life-threatening disease primarily caused by a metabolic disorder and an altered immune response in the bone marrow (BM) microenvironment, where cytotoxic immune cells attack resident cells and lead to hematopoietic failure. We previously reported an efficient strategy by a...

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Detalles Bibliográficos
Autores principales: Wang, Jiali, Liu, Jia, Wang, Mingyang, Zhao, Fei, Ge, Meili, Liu, Li, Jiang, Erlie, Feng, Sizhou, Han, Mingzhe, Pei, Xiaolei, Zheng, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331934/
https://www.ncbi.nlm.nih.gov/pubmed/35911766
http://dx.doi.org/10.3389/fimmu.2022.907808