An Integrated Proteomic and Glycoproteomic Investigation Reveals Alterations in the N-Glycoproteomic Network Induced by 2-Deoxy-D-Glucose in Colorectal Cancer Cells

As a well-known glycolysis inhibitor for anticancer treatment, 2-Deoxy-D-glucose (2DG) inhibits the growth and survival of cancer cells by interfering with the ATP produced by the metabolism of D-glucose. In addition, 2DG inhibits protein glycosylation in vivo by competing with D-mannose, leading to...

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Detalles Bibliográficos
Autores principales: Ma, Cheng, Tsai, Hong-Yuan, Zhang, Qi, Senavirathna, Lakmini, Li, Lian, Chin, Lih-Shen, Chen, Ru, Pan, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331968/
https://www.ncbi.nlm.nih.gov/pubmed/35897829
http://dx.doi.org/10.3390/ijms23158251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331968/
https://www.ncbi.nlm.nih.gov/pubmed/35897829
http://dx.doi.org/10.3390/ijms23158251

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