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A NanoBRET-Based H(3)R Conformational Biosensor to Study Real-Time H(3) Receptor Pharmacology in Cell Membranes and Living Cells

Conformational biosensors to monitor the activation state of G protein-coupled receptors are a useful addition to the molecular pharmacology assay toolbox to characterize ligand efficacy at the level of receptor proteins instead of downstream signaling. We recently reported the initial characterizat...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyuan, Gao, Meichun, Vischer, Henry F., Leurs, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332000/
https://www.ncbi.nlm.nih.gov/pubmed/35897787
http://dx.doi.org/10.3390/ijms23158211