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The mTOR Signaling Pathway in Multiple Sclerosis; from Animal Models to Human Data

This article recapitulates the evidence on the role of mammalian targets of rapamycin (mTOR) complex pathways in multiple sclerosis (MS). Key biological processes that intersect with mTOR signaling cascades include autophagy, inflammasome activation, innate (e.g., microglial) and adaptive (B and T c...

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Detalles Bibliográficos
Autores principales: Vakrakou, Aigli G., Alexaki, Anastasia, Brinia, Maria-Evgenia, Anagnostouli, Maria, Stefanis, Leonidas, Stathopoulos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332053/
https://www.ncbi.nlm.nih.gov/pubmed/35897651
http://dx.doi.org/10.3390/ijms23158077