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The mTOR Signaling Pathway in Multiple Sclerosis; from Animal Models to Human Data
This article recapitulates the evidence on the role of mammalian targets of rapamycin (mTOR) complex pathways in multiple sclerosis (MS). Key biological processes that intersect with mTOR signaling cascades include autophagy, inflammasome activation, innate (e.g., microglial) and adaptive (B and T c...
Autores principales: | Vakrakou, Aigli G., Alexaki, Anastasia, Brinia, Maria-Evgenia, Anagnostouli, Maria, Stefanis, Leonidas, Stathopoulos, Panos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332053/ https://www.ncbi.nlm.nih.gov/pubmed/35897651 http://dx.doi.org/10.3390/ijms23158077 |
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