Cargando…

HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny

Cancer stem cells (CSCs) are in general characterized by higher resistance to cell death and cancer therapies than non-stem differentiated cancer cells. However, we and others have recently revealed using glioma stem cells (GSCs) as a model that, unexpectedly, CSCs have specific vulnerabilities that...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakagawa-Saito, Yurika, Saitoh, Shinichi, Mitobe, Yuta, Sugai, Asuka, Togashi, Keita, Suzuki, Shuhei, Kitanaka, Chifumi, Okada, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332065/
https://www.ncbi.nlm.nih.gov/pubmed/35897656
http://dx.doi.org/10.3390/ijms23158084