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Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids

The plasma membrane (PM) stability of the cystic fibrosis transmembrane conductance regulator (CFTR), the protein which when mutated causes Cystic Fibrosis (CF), relies on multiple interaction partners that connect CFTR to signaling pathways, including cAMP signaling. It was previously shown that ac...

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Detalles Bibliográficos
Autores principales: Ferreira, João F., Silva, Iris A. L., Botelho, Hugo M., Amaral, Margarida D., Farinha, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332071/
https://www.ncbi.nlm.nih.gov/pubmed/35892592
http://dx.doi.org/10.3390/cells11152295