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MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice

MHCII molecules, expressed by professional antigen-presenting cells (APCs) such as T cells and B cells, are hypothesized to play a key role in the response of cellular immunity to α-synuclein (α-syn). However, the role of cellular immunity in the neuroanatomic transmission of α-syn pre-formed fibril...

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Detalles Bibliográficos
Autores principales: Gonzalez De La Cruz, Elsa, Vo, Quan, Moon, Katie, McFarland, Karen N., Weinrich, Mary, Williams, Tristan, Giasson, Benoit I., Chakrabarty, Paramita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332117/
https://www.ncbi.nlm.nih.gov/pubmed/35897751
http://dx.doi.org/10.3390/ijms23158175