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Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer

Prostate cancer is the most common cancer in men, and it is primarily driven by androgen steroid hormones. The glycosylation enzyme EDEM3 is controlled by androgen signalling and is important for prostate cancer viability. EDEM3 is a mannosidase that trims mannose from mis-folded glycoproteins, tagg...

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Detalles Bibliográficos
Autores principales: Scott, Emma, Garnham, Rebecca, Cheung, Kathleen, Duxfield, Adam, Elliott, David J., Munkley, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332126/
https://www.ncbi.nlm.nih.gov/pubmed/35897761
http://dx.doi.org/10.3390/ijms23158184