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Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer
Prostate cancer is the most common cancer in men, and it is primarily driven by androgen steroid hormones. The glycosylation enzyme EDEM3 is controlled by androgen signalling and is important for prostate cancer viability. EDEM3 is a mannosidase that trims mannose from mis-folded glycoproteins, tagg...
Autores principales: | Scott, Emma, Garnham, Rebecca, Cheung, Kathleen, Duxfield, Adam, Elliott, David J., Munkley, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332126/ https://www.ncbi.nlm.nih.gov/pubmed/35897761 http://dx.doi.org/10.3390/ijms23158184 |
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