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Mapping Transcriptomic Vector Fields of Single Cells

Single-cell (sc)-RNA-seq, together with RNA-velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires kinetic models capable of unveiling governing regulatory functions. Here, we introduce an analytical framew...

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Detalles Bibliográficos
Autores principales: Qiu, Xiaojie, Zhang, Yan, Martin-Rufino, Jorge D., Weng, Chen, Hosseinzadeh, Shayan, Yang, Dian, Pogson, Angela N., Hein, Marco Y., Min, Kyung Hoi (Joseph), Wang, Li, Grody, Emanuelle I., Shurtleff, Matthew J., Yuan, Ruoshi, Xu, Song, Ma, Yian, Replogle, Joseph M., Lander, Eric S., Darmanis, Spyros, Bahar, Ivet, Sankaran, Vijay G., Xing, Jianhua, Weissman, Jonathan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332140/
https://www.ncbi.nlm.nih.gov/pubmed/35108499
http://dx.doi.org/10.1016/j.cell.2021.12.045