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Mapping Transcriptomic Vector Fields of Single Cells
Single-cell (sc)-RNA-seq, together with RNA-velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires kinetic models capable of unveiling governing regulatory functions. Here, we introduce an analytical framew...
Autores principales: | Qiu, Xiaojie, Zhang, Yan, Martin-Rufino, Jorge D., Weng, Chen, Hosseinzadeh, Shayan, Yang, Dian, Pogson, Angela N., Hein, Marco Y., Min, Kyung Hoi (Joseph), Wang, Li, Grody, Emanuelle I., Shurtleff, Matthew J., Yuan, Ruoshi, Xu, Song, Ma, Yian, Replogle, Joseph M., Lander, Eric S., Darmanis, Spyros, Bahar, Ivet, Sankaran, Vijay G., Xing, Jianhua, Weissman, Jonathan S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332140/ https://www.ncbi.nlm.nih.gov/pubmed/35108499 http://dx.doi.org/10.1016/j.cell.2021.12.045 |
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