Effects of the Calix[4]arene Derivative Compound OTX008 on High Glucose-Stimulated ARPE-19 Cells: Focus on Galectin-1/TGF-β/EMT Pathway

Diabetic retinopathy (DR) is a neurovascular disease characterized by the reduction of retina integrity and functionality, as a consequence of retinal pigment epithelial cell fibrosis. Although galectin-1 (a glycan-binding protein) has been associated with dysregulated retinal angiogenesis, no evide...

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Detalles Bibliográficos
Autores principales: Trotta, Maria Consiglia, Petrillo, Francesco, Gesualdo, Carlo, Rossi, Settimio, Corte, Alberto Della, Váradi, Judit, Fenyvesi, Ferenc, D’Amico, Michele, Hermenean, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332238/
https://www.ncbi.nlm.nih.gov/pubmed/35897964
http://dx.doi.org/10.3390/molecules27154785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332238/
https://www.ncbi.nlm.nih.gov/pubmed/35897964
http://dx.doi.org/10.3390/molecules27154785

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