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Effects of the Calix[4]arene Derivative Compound OTX008 on High Glucose-Stimulated ARPE-19 Cells: Focus on Galectin-1/TGF-β/EMT Pathway
Diabetic retinopathy (DR) is a neurovascular disease characterized by the reduction of retina integrity and functionality, as a consequence of retinal pigment epithelial cell fibrosis. Although galectin-1 (a glycan-binding protein) has been associated with dysregulated retinal angiogenesis, no evide...
Autores principales: | Trotta, Maria Consiglia, Petrillo, Francesco, Gesualdo, Carlo, Rossi, Settimio, Corte, Alberto Della, Váradi, Judit, Fenyvesi, Ferenc, D’Amico, Michele, Hermenean, Anca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332238/ https://www.ncbi.nlm.nih.gov/pubmed/35897964 http://dx.doi.org/10.3390/molecules27154785 |
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