Itraconazole Nanosuspensions via Dual Centrifugation Media Milling: Impact of Formulation and Process Parameters on Particle Size and Solid-State Conversion as Well as Storage Stability

Nanocrystal suspensions proved to be a potent enabling principle for biopharmaceutics classification system class II drugs with dissolution limited bioavailability. In the example of itraconazole (ITZ) as a model drug combined with electrosteric stabilization using hydroxypropyl cellulose (HPC-SL),...

Descripción completa

Detalles Bibliográficos
Autores principales: Willmann, Ann-Cathrin, Berkenfeld, Kai, Faber, Thilo, Wachtel, Herbert, Boeck, Georg, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332252/
https://www.ncbi.nlm.nih.gov/pubmed/35893783
http://dx.doi.org/10.3390/pharmaceutics14081528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332252/
https://www.ncbi.nlm.nih.gov/pubmed/35893783
http://dx.doi.org/10.3390/pharmaceutics14081528

Ejemplares similares