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Itraconazole Nanosuspensions via Dual Centrifugation Media Milling: Impact of Formulation and Process Parameters on Particle Size and Solid-State Conversion as Well as Storage Stability

Nanocrystal suspensions proved to be a potent enabling principle for biopharmaceutics classification system class II drugs with dissolution limited bioavailability. In the example of itraconazole (ITZ) as a model drug combined with electrosteric stabilization using hydroxypropyl cellulose (HPC-SL),...

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Detalles Bibliográficos
Autores principales:	Willmann, Ann-Cathrin, Berkenfeld, Kai, Faber, Thilo, Wachtel, Herbert, Boeck, Georg, Wagner, Karl G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332252/ https://www.ncbi.nlm.nih.gov/pubmed/35893783 http://dx.doi.org/10.3390/pharmaceutics14081528

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