mTORC1 and mTORC2 Complexes Regulate the Untargeted Metabolomics and Amino Acid Metabolites Profile through Mitochondrial Bioenergetic Functions in Pancreatic Beta Cells

Background: Pancreatic beta cells regulate bioenergetics efficiency and secret insulin in response to glucose and nutrient availability. The mechanistic Target of Rapamycin (mTOR) network orchestrates pancreatic progenitor cell growth and metabolism by nucleating two complexes, mTORC1 and mTORC2. Ob...

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Detalles Bibliográficos
Autores principales: Soliman, Ghada A., Abzalimov, Rinat R., He, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332257/
https://www.ncbi.nlm.nih.gov/pubmed/35893876
http://dx.doi.org/10.3390/nu14153022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332257/
https://www.ncbi.nlm.nih.gov/pubmed/35893876
http://dx.doi.org/10.3390/nu14153022

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