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Folding and Binding Mechanisms of the SH2 Domain from Crkl

SH2 domains are structural modules specialized in the recognition and binding of target sequences containing a phosphorylated tyrosine residue. They are mostly incorporated in the 3D structure of scaffolding proteins that represent fundamental regulators of several signaling pathways. Among those, C...

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Detalles Bibliográficos
Autores principales: Nardella, Caterina, Toto, Angelo, Santorelli, Daniele, Pagano, Livia, Diop, Awa, Pennacchietti, Valeria, Pietrangeli, Paola, Marcocci, Lucia, Malagrinò, Francesca, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332313/
https://www.ncbi.nlm.nih.gov/pubmed/35892324
http://dx.doi.org/10.3390/biom12081014