Low-Dose-Rate Radiation-Induced Secretion of TGF-β3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding

Hyper-radiosensitivity (HRS) is the increased sensitivity to low doses of ionizing radiation observed in most cell lines. We previously demonstrated that HRS is permanently abolished in cells irradiated at a low dose rate (LDR), in a mechanism dependent on transforming growth factor β3 (TGF-β3). In...

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Detalles Bibliográficos
Autores principales: Hanson, Ingunn, Pitman, Kathinka E., Altanerova, Ursula, Altaner, Čestmír, Malinen, Eirik, Edin, Nina F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332371/
https://www.ncbi.nlm.nih.gov/pubmed/35897723
http://dx.doi.org/10.3390/ijms23158147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332371/
https://www.ncbi.nlm.nih.gov/pubmed/35897723
http://dx.doi.org/10.3390/ijms23158147

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