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Low-Dose-Rate Radiation-Induced Secretion of TGF-β3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding
Hyper-radiosensitivity (HRS) is the increased sensitivity to low doses of ionizing radiation observed in most cell lines. We previously demonstrated that HRS is permanently abolished in cells irradiated at a low dose rate (LDR), in a mechanism dependent on transforming growth factor β3 (TGF-β3). In...
Autores principales: | Hanson, Ingunn, Pitman, Kathinka E., Altanerova, Ursula, Altaner, Čestmír, Malinen, Eirik, Edin, Nina F. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332371/ https://www.ncbi.nlm.nih.gov/pubmed/35897723 http://dx.doi.org/10.3390/ijms23158147 |
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