The Molecular Mechanisms of Actions, Effects, and Clinical Implications of PARP Inhibitors in Epithelial Ovarian Cancers: A Systematic Review

Ovarian cancer is the most lethal gynecologic malignancy in the United States. Some patients affected by ovarian cancers often present genome instability with one or more of the defects in DNA repair pathways, particularly in homologous recombination (HR), which is strictly linked to mutations in br...

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Detalles Bibliográficos
Autores principales: Lau, Chien-Hui, Seow, Kok-Min, Chen, Kuo-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332395/
https://www.ncbi.nlm.nih.gov/pubmed/35897700
http://dx.doi.org/10.3390/ijms23158125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332395/
https://www.ncbi.nlm.nih.gov/pubmed/35897700
http://dx.doi.org/10.3390/ijms23158125

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