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Efficacy of Topically Administered Dihydroartemisinin in Treating Papillomavirus-Induced Anogenital Dysplasia in Preclinical Mouse Models

The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated the efficacy of topical dihydroartemisinin (DHA) on cervical dysplasia and anal dysplasia in...

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Detalles Bibliográficos
Autores principales: Gunder, Laura C., Blaine-Sauer, Simon, Johnson, Hillary R., Shin, Myeong-Kyun, Auyeung, Andrew S., Zhang, Wei, Leverson, Glen E., Ward-Shaw, Ella T., King, Renee E., McGregor, Stephanie M., Matkowskyj, Kristina A., Lambert, Paul F., Carchman, Evie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332511/
https://www.ncbi.nlm.nih.gov/pubmed/35893697
http://dx.doi.org/10.3390/v14081632