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Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted Patients

Immunosuppressant drugs (ISDs) are routinely used in clinical practice to maintain organ transplant survival. However, these drugs are characterized by a restricted therapeutic index, a high inter- and intra-individual pharmacokinetic variability, and a series of severe adverse effects. In particula...

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Detalles Bibliográficos
Autores principales: Urzì Brancati, Valentina, Scarpignato, Carmelo, Minutoli, Letteria, Pallio, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332547/
https://www.ncbi.nlm.nih.gov/pubmed/35892699
http://dx.doi.org/10.3390/biomedicines10081798