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An Intramolecular Hydroaminomethylation-Based Approach to Pyrrolizidine Alkaloids under Microwave-Assisted Heating

A general method for the synthesis of pyrrolizidine derivatives using an intramolecular hydroaminomethylation protocol (HAM) under microwave (MW) dielectric heating is reported. Starting from a 3,4-bis(benzyloxy)-2-[(benzyloxy)methyl]-5-vinylpyrrolidine, MW-assisted intramolecular HAM in the presenc...

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Detalles Bibliográficos
Autores principales: Petricci, Elena, Zurzolo, Simone, Matassini, Camilla, Maramai, Samuele, Cardona, Francesca, Goti, Andrea, Taddei, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332719/
https://www.ncbi.nlm.nih.gov/pubmed/35897934
http://dx.doi.org/10.3390/molecules27154762