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Farnesol Boosts the Antifungal Effect of Fluconazole and Modulates Resistance in Candida auris through Regulation of the CDR1 and ERG11 Genes

Candida auris is considered a serious fungal pathogen frequently exhibiting a high resistance to a wide range of antifungals. In this study, a combination of the quorum-sensing molecule farnesol (FAR) and fluconazole (FLU) was tested on FLU-resistant C. auris isolates (C. auris S and C. auris R) com...

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Detalles Bibliográficos
Autores principales: Dekkerová, Jaroslava, Černáková, Lucia, Kendra, Samuel, Borghi, Elisa, Ottaviano, Emerenziana, Willinger, Birgit, Bujdáková, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9332773/
https://www.ncbi.nlm.nih.gov/pubmed/35893151
http://dx.doi.org/10.3390/jof8080783